OCTREOTIDE

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139
OCTROTIDE
CALCUTIONS AREA
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Infant Data

Results

MEDICAL INFORMATIONS

INDICATIONS

  • Refractory hyperinsulinemic hypoglycemia.
  • Congenital and postoperative chylothorax, Adjunct.

ADVERSE EFFECTS

  • Vomiting, diarrhea, abdominal distention and steatorrhea may occur.
  • Pulmonary hypertension has been reported in treated former premature infants with chronic lung disease.
  • Necrotizing enterocolitis has been reported in term neonates receiving octreotide for the treatment of hyperinsulinemic hypoglycemia (6 cases) and chylothorax (2 cases).
  • Hyperglycemia may occur in patients being treated for chylothorax.

ADMINISTRATION

  • Subcutaneous: To minimize pain, use smallest volume to deliver dose. Rotate sites.
  • Intravenous:
    • May give IV push over 3 minutes (or rapid IV bolus in emergency situations) or by intermittent IV infusion over 15 to 30 minutes in compatible solution at a concentration of 10 to 25 mcg/mL.
    • May also give by continuous IV infusion. Dilutions as low as 1 mcg/mL can be used.

MONITORING

  • Monitor blood glucose closely.
  • Monitor for signs and symptoms of necrotizing enterocolitis.