Infant Data
Results
INDICATIONS
- Treatment of torsades de pointes: Treatment of torsades de pointes (polymorphic ventricular tachycardia associated with long QT interval).The American Heart Association(AHA) did not review the use of magnesium in the 2015 Neonatal Resuscitation guidelines; therefore, the 2010 AHA guidelines still apply. < /li>
- Treatment and prevention of hypomagnesemia:
CONTRAINDICATIONS / PRECAUTIONS
Contraindicated in patients with heart block or myocardial damage. Hypotension and bradycardia may occur with rapid infusion. Calcium chloride should be available to reverse magnesium toxicity. Use with caution in patients with renal impairment since magnesium sulfate is eliminated renally. Respiratory depression may occur from high magnesium levels. Contains aluminum which may be toxic, especially in premature neonates and patients with renal impairment.
ADVERSE EFFECTS
Flushing, sweating, hypothermia, and stupor may occur. Low calcium levels or bone problems, including osteopenia or fractures, may occur in developing baby or fetus following prolonged use (greater than 5 to 7 days) of magnesium sulfate for stopping pre-term labor in pregnant mothers.
ADMINISTRATION
Must be diluted prior to IV administration to a concentration of 100 to 200 mg/mL. Give by rapid infusion (over several minutes) for pulseless torsades, over 10 to 20 minutes for hypomagnesemia/torsades with pulses, and over 30 to 60 minutes for hypomagnesemia.
MONITORING
Monitor serum and urinary magnesium levels. Assess other electrolytes (calcium, potassium, phosphorus) and renal function periodically..