CALCUTIONS AREA
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Infant Data
Results
MEDICAL INFORMATIONS
INDICATIONS
Treatment of mild to moderate neonatal hypertension by vasodilation. Afterload reduction in patients with congestive heart failure.
ADVERSE EFFECTS
Diarrhea, emesis, and temporary agranulocytosis have been reported in neonates. Tachycardia, postural hypotension, headache, nausea, and a lupus-like syndrome occur in 10% to 20% of adults. Uncommon reactions in adults include GI irritation and bleeding, drug fever, rash, conjunctivitis, and bone marrow suppression.
ADMINISTRATION
Intravenous: Administer undiluted (20 mg/mL) over 30 seconds to 2 minutes. Further dilution (ie, 1 mg/mL) may be necessary.
MONITORING
Frequent assessment of blood pressure and heart rate. Guaiac stools. Periodic CBC during long-term use.