FOLIC ACID

160
FOLIC ACID
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Infant Data

Results

MEDICAL INFORMATIONS

INDICATIONS

Supplementation may be needed in low-birth-weight infants, in infants who are breast-fed by a mother with folic acid deficiency, infants with infections, or infants with prolonged diarrhea.

CONTRAINDICATIONS

  • Previous intolerance to the drug.

PRECAUTIONS

  • Administration:
    • Higher than recommended doses (above 0.1 mg/day) may obscure pernicious anemia.
  • Benzyl alcohol:
    • Parenteral product contains benzyl alcohol which has been associated with fatal gasping syndrome in premature infants.
  • Hematologic:
    • Folic acid monotherapy is not sufficient for treatment of pernicious anemia or other megaloblastic anemias when vitamin B12 is deficient.
  • Toxicity:
    • Aluminum toxicity may occur with prolonged parenteral administration, particularly in premature neonates and in patients with impaired renal function. Parental doses of aluminum greater than 4 to 5 mcg/kg/day may result in CNS or bone toxicity.

ADVERSE EFFECTS

Allergic sensitization has occurred with both oral and parenteral administration of folic acid.

ADMINISTRATION

May administer as IM, IV, or subQ injection; oral route is preferred.