FDA APPROVED INDICATION
As a diagnostic agent in the screening of patients presumed to have adrenocortical insufficiency.
CONTRAINDICATIONS
Previous adverse reaction to cosyntropin.
PRECAUTIONS
- Immunologic:
- Acute hypersensitivity reaction, including anaphylaxis, is possible.
ADVERSE EFFECTS
Bradycardia, tachycardia, hypertension, peripheral edema, and rash.
ADMINISTRATION
- IV: Dilute dose in 2 to 5 mL sodium chloride and administer over 2 minutes. To minimize loss of drug in tubing when using a low dose (1 mcg), consider using a 2.5 cm plastic tube rather than long IV plastic tubing and follow the dose with 5 mL normal saline flush.
- IV Infusion: Dilute dose in glucose or sodium chloride and infuse over 4 to 8 hours
MONITORING
Concurrent use with cortisone, hydrocortisone, spironolactone, or estrogen may alter the test results.
CALCULATIONS AREA
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