CALCUTIONS AREA
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Infant Data
Results
MEDICAL INFORMATIONS
INDICATIONS
- treatment of skin, intra-abdominal and urinary tract infections: Use in neonates is generally limited to treatment of skin, intra-abdominal and urinary tract infections caused by susceptible bacteria – anaerobes (e.g. Bacteroides fragilis), gram positives (e.g. Staphylococcus aureus, Streptococcus pneumoniae, and other streptococci except enterococcus) and gram negatives (e.g. Haemophilus influenzae, Klebsiella species, E. coli, Proteus vulgaris, and Neisseria gonorrhoeae).
ADVERSE EFFECTS
Adverse effects are rare. Transient eosinophilia and elevation of hepatic transaminases have been reported in less than 3% of treated patients. Severe overdose can cause tachypnea, pallor, hypotonia, and metabolic acidosis.
ADMINISTRATION
Give as an intermittent IV infusion at a concentration of 10 to 40 mg/mL over 15 to 60 minutes.
MONITORING
Serum concentrations are not routinely monitored.