CALCUTIONS AREA
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Results
MEDICAL INFORMATIONS
INDICATIONS
Prevention of vitamin E deficiency. May be indicated in babies receiving erythropoietin and high iron dosages. Higher doses used to reduce oxidant-induced injury (ROP, BPD, IVH) remain controversial.
ADVERSE EFFECTS
Feeding intolerance may occur due to hyperosmolarity of preparation. Pharmacologic doses of alpha tocopherol have been associated with increased rates of sepsis (antioxidant effect of drug) and NEC (osmolarity of oral formulation).
MONITORING
Assess feeding tolerance. Signs of vitamin E deficiency include hemolytic anemia and thrombocytosis. Physiologic serum vitamin E concentrations are between 0.8 and 3.5 mg/dL.