Infant Data
Results
INDICATIONS
Limited to treatment of infections caused by gram positive organisms resistant to other antibiotics, eg, methicillin-resistant Staph aureus and vancomycin-resistant Enterococcus faecium (not E faecalis).
ADVERSE EFFECTS
Myalgias and arthralgias occur frequently in adults with hepatic or renal failure. Elevations in serum bilirubin and transaminases are common. Diarrhea and rash occur infrequently.
ADMINISTRATION
Give by intermittent IV infusion over 60 minutes at a concentration of 2 mg/mL. A concentration up to 5 mg/mL may be used for central lines. Concentrations less than 1 mg/mL may be used if venous irritation occurs following peripheral administration. Flush peripheral line with D5W before infusion if other drugs are administered through the same IV line, and after infusion to minimize venous irritation. Infusion through a central line will decrease the risk for venous irritation. Do not flush with saline or heparin due to incompatibility
MONITORING
Periodic measurement of serum bilirubin and transaminases. Assess peripheral IV site for signs of inflammation.